KOR

WHITENING

01. Skin Whitening and Natural Extract

The botanical whitening active ingredient inhibits tyrosine kinase, the main enzyme of melanogenesis,

as well as inhibits melanin production from melanocytes.

Due to the "Dual-Mechanism" of these botanical whitening active ingredients, it keeps the blackened skin healthy, clear and white skin.

Skin whitening and whitening complex™

피부 미백과 화이트닝 콤플렉스™

02. Melanin Production Inhibition Evaluation

Melanoma cells were cultured in the presence of GluCA® and the total amount of melanin

synthesized in the cells was reduced by 37% compared to non-treatment group as a control.

Analysis of total melanin levels in melanoma cells treated with GluCA®

*represents a statistically significant difference between the treated and the control (p < 0.05)

03. Tyrosinase Inhibition Test

The inhibitory effect of tyrosinase, the most important enzyme of melanin synthesis,

examined in melanoma cells treated with GluCA®.

That is, 69%, 51% and 48% inhibition of enzyme activity was observed in the treatment groups of 1 μg/ml, 5 μg/ml and 10 μg/ml, respectively.

Tyrosinase inhibition assay by GluCA®

*represents a statistically significant difference between the treated and the control (p < 0.05)

04. Skin Whitening Effects Evaluation

GluCA® Cure has proven the whitening, regeneration & restoration of melanin pigmentation skin by a variety of causes

through three-dimensional melanocyte cell culture experiments and skin clinical testing

Evaluation of the whitening effects of natural extracts

  • Melanin accumulation - purple

  • Contrast group  

  • UV B  

  • UV B + Natural extract

Skin Whitening Clinical Efficacy Assessment

  • GluCA® Melanin pigment inhibition

  • Before use

  • After 4 weeks

  • After 8 weeks

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